Clinical Trials

  • Principal Investigator:

    Uma M. Reddy, MD, MPH
    This research study is being done to is to understand how CPAP for sleep apnea may affect hypertensive disorders of pregnancy and other complications of pregnancy such as gestational diabetes. The purpose of the home sleep test is to find women with sleep apnea. Sleep apnea is when you have one or more pauses in breathing or shallow breaths while you sleep. Studies have shown that women with sleep apnea have an increased risk of high blood pressure and diabetes during pregnancy. If the test shows that you have sleep apnea in the mild to moderate range you will be eligible for a research study...
  • Principal Investigator:

    June Y. Hou, MD
    The purpose of the first part of this study, the Dose Escalation part, is to study and identify the highest tolerable safe dose of MORAb-202. Not all patients will get the same dose of the study drug. At the beginning of the study, a small group of three to six patients will receive an infusion with a low dose of the study drug. If this dose does not cause severe side effects, it will be increased for each new group of patients who participate in the study and will continue until the highest tolerable safe dose of the drug is confirmed. This dose will be selected and used as the starting dose...
  • Principal Investigator:

    Carolyn L. Westhoff, MD
    If you are sexually active, have normal, regular menstrual cycles, do not wish to become pregnant for at least 12 months, and are willing to try an investigational hormonal method of birth control, then you may be eligible to join the LUMINOUS Study. This study will investigate whether an investigational contraceptive patch, worn on the skin, can prevent pregnancy in women. To take part in the study, you must be willing and able to use the study patch as your only method of birth control, apply the study patch at home and undertake home pregnancy tests, complete an electronic diary with...
  • Principal Investigator:

    Catherine Monk, PHD
    We are working to address the racial disparities in birth outcomes, a pressing issue in women's health research. In particular, we want to better understand the role that mood, stress, and inflammation play in the development of your baby. In our study, participants are asked to engage in up to 3 in-person prenatal sessions at Columbia University Medical Center (168th Street). These sessions are expected to take up to 4.5 hours total. You will have blood drawn and provide hair and saliva samples. At the third trimester session, participants will play a word and color matching game while we...
  • Principal Investigator:

    June Y. Hou, MD
    This research study has two parts. Participants will be enrolled in the second part of the study. The names of the study drugs are RGX-104, nivolumab, ipilimumab, docetaxel, carboplatin, and pemetrexed. The purpose of the first part of the study is to determine the highest dose of RGX-104 the body can handle. The purpose of the second part is to determine if the highest dose of RGX-104 determined in the first part might be an effective treatment option for people with advanced cancers. Both parts of the study will try to understand the safety and side effects of RGX-104.
  • Principal Investigator:

    Jason D. Wright, MD
    We are doing this study because we want to find out if adding a new immunotherapy drug to the usual combination of chemotherapy drugs is better or worse than the usual approach for your endometrial cancer. The usual approach is defined as care most people get for endometrial cancer.
  • Principal Investigator:

    Catherine Monk, PHD
    Do you ever wish there was more information on how to handle the challenges of pregnancy and having a new baby? This study looks into whether certain behavioral techniques used by mothers can help their babies sleep more and cry less and, in turn, improve womens moods and child outcomes. The study starts when you are in your third trimester of pregnancy and lasts until your baby is about 4 months old. After you attend a virtual screening session by phone or video to determine that you are fully eligible for the study, you will have 4 virtual sessions by phone or video; 1) at 28-32 weeks of...
  • Principal Investigator:

    Catherine Monk, PHD
    Do you ever wish there was more information on how to handle the challenges of pregnancy and having a new baby? This study looks into whether certain behavioral techniques used by mothers can help their babies sleep more and cry less and, in turn, improve womens moods and child outcomes. The study starts when you are in your third trimester of pregnancy and lasts until your baby is about 4 months old. After you attend a virtual screening session by phone or video to determine that you are fully eligible for the study, you will have 4 virtual sessions by phone or video; 1) at 28-32 weeks of...
  • Principal Investigator:

    Carolyn L. Westhoff, MD
    The study is looking to evaluate levonogestrel butanoate as a possible new long-acting injectable for birth control. Levonogestrel butanoate is a type of hormone called progestin that has a long history of clinical use in a variety of birth control methods (e.g. pills, intrauterine devices, implants) and its efficacy and safety are well recognized. This study is seeking for healthy female volunteers between the ages of 18-40 years of age. Participation time is estimated to last up to 9 months with approximately 36 study visits. The first visit will last about 1 hour and all other visits will...