The Division of Family Planning and Preventive Services has many active clinical trials involving the development and assessment of contraceptive methods; these studies range from Phase I to Phase IV. We also study approaches to improved abortion care and innovations in reproductive health screening.

The Division is one of twelve centers nationwide that participate in the Contraceptive Clinical Trials Network (CCTN) of the National Institute of Health, developing new methods of birth control. All of our research is patient-centered and is designed to bring contraceptive innovations to patients as quickly as possible. New trials in the CCTN include:

  • Clinical evaluation of nestorone/estradiol releasing vaginal ring for female contraception
  • A multicenter, randomized study on the serum estradiol levels, efficacy, cycle control, and safety of a contraceptive vaginal ring delivering a daily dose of Nesterone® and esteradiol (NES-E2 CVR)
  • A multi-center, randomized study to evaluate the pharmacokinetic and pharmacodynamic profile, effects on the mechanisms of contraceptive efficacy, and safety of daily oral low dose ulipristal acetate
  • Randomized trial to determine effectiveness, insertion characteristics and side effects of copper intrauterine devices
  • Three arm emergency contraception study on Ella, Plan B, and double dose Plan B in obese women
  • Clinical evaluation of levonorgestrel butanoate for female contraception

The Division is also home to pilot studies, foundation sponsored projects, as well as larger multi-center trials funded by NIH and industry sponsors. Current and recent trials include:

  • Safety and effectiveness of Essure™ Model Ess505
  • Bilateral tubal occlusive trial for female permanent contraception
  • Contraceptive efficacy and safety of etonogestrel (MK-8415) implant during extended use from 3 years after insertion in females 35 years of age or younger

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