Hemant Suryawanshi, PhD
- Assistant Professor of Reproductive Sciences (in Obstetrics and Gynecology) at CUMC
On the web
Overview
Hemant Suryawanshi, PhD, is an Assistant Professor of Reproductive Sciences at Columbia University Medical Center (CUMC) in the Department of Obstetrics and Gynecology.
Academic Appointments
- Assistant Professor of Reproductive Sciences (in Obstetrics and Gynecology) at CUMC
Credentials & Experience
Education & Training
- BSc, 2006 Microbiology, Shivaji University, India
- MSc, 2008 Microbiology, University of Pune, India
- PhD, 2015 Biotechnology, Institute of Genomics and Integrative Biology, New Delhi, India
- Fellowship: 2012 Rockefeller University, New York, NY
- Fellowship: 2013 Institute of Genomics and Integrative Biology, New Delhi, India
Research
At the intersection of biology, AI, and microfluidics - developing precision tools for fertility care and early fetal diagnostics.
Dr. Suryawanshi is an assistant professor and faculty member at Columbia University Fertility Center (CUFC), where he is a lead researcher in the CUFC Research & Development laboratory. There, he played a central role in developing the STAR (Sperm Tracking and Recovery) system, an AI-powered microfluidic platform integrated with high-speed imaging to identify and recover rare sperm in patients with azoospermia and cryptozoospermia. STAR enabled the world’s first successful AI-assisted human conception, resulting in a clinical pregnancy using sperm identified and recovered by the system. The technology is now offered as a clinical service at CUFC.
Dr. Suryawanshi’s research focuses on building next-generation tools to address complex challenges in reproductive medicine. His interdisciplinary work integrates artificial intelligence, microfluidics, single-cell biology, and computer vision to advance diagnostics, therapeutics, and personalized care.
Prior to joining Columbia, Dr. Suryawanshi conducted pioneering research at Rockefeller University using single-cell transcriptomics to profile human tissues including fetal heart, skin, kidney, placenta, decidua, and testis in conditions such as lupus nephritis, atopic dermatitis, transplantation, and congenital heart block.
Research Interests
- Computer Vision
- Male Infertility
- Microfluidics
- Preeclampsia
- Single-cell Biology
Selected Publications
- Suryawanshi H, Morozov P, Straus A, Sahasrabudhe N, Max KEA, Garzia A, Kustagi M, Tuschl T, Williams Z. A single-cell survey of the human first-trimester placenta and decidua. Science Advances. 2018 Oct 31;4(10):eaau4788.
- Der E*, Suryawanshi H*, Morozov P, Kustagi M, Goilav B, Ranabothu S, Izmirly P, Clancy R, Belmont HM, Koenigsberg M, Mokrzycki M, Rominieki H, Graham JA, Rocca JP, Bornkamp N, Jordan N, Schulte E, Wu M, Pullman J, Slowikowski K, Raychaudhuri S, Guthridge J, James J, Buyon J, Tuschl T, Putterman C; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium. Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways. Nature Immunology. 2019 Jul;20(7):915-927.
- Suryawanshi H, Clancy R, Morozov P, Halushka MK, Buyon JP, Tuschl T. Cell atlas of the foetal human heart and implications for autoimmune-mediated congenital heart block. Cardiovascular research. 2020 Jul 1;116(8):1446-1457.
- Yamaji M, Jishage M, Meyer C, Suryawanshi H, Der E, Yamaji M, Garzia A, Morozov P, Manickavel S, McFarland HL, Roeder RG, Hafner M, Tuschl T. DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs. Nature. 2017 Mar 23;543(7646):568-572.
- He H*, Suryawanshi H*†, Morozov P, Gay-Mimbrera J, Del Duca E, Kim HJ, Kameyama N, Estrada Y, Der E, Krueger JG, Ruano J, Tuschl T†, Guttman-Yassky E†. Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis. Journal of Allergy and Clinical Immunology. 2020 Jun;145(6):1615-1628.
- Suryawanshi H†, Yang H, Lubetzky M, Morozov P, Lagman M, Alonso A, Li C, Snopkowski C, Mueller FB, Lee JR, Dadhania DM, Salvatore SP, Seshan SV, Sharma VK, Suthanthiran M, Tuschl T†, Muthukumar T†. Detection of infiltrating fibroblasts by single-cell transcriptomics in human kidney allografts. PLOS One. 2022 17(6): e0267704.
* Authors contributed equally (co-first-authors)
† Co-corresponding-authors
For a complete list of publications, please visit PubMed.gov